You might still remember the little firefox tweak that reduced memory usage when minimizing firefox. Gomeler.com has some more tips that optimise firefox even more. Lets take a look at them, shall we ?
Back Button Hack:
Before using this hack I went to Cnn.com and entered 10 different articles but never touched the back button, just using links. Upon the 10th article, Firefox was using 41Mb. I performed the hack and performed the same step by visiting the same sites with a cleared Cache, and memory usage was down to 33.7 Mb. This value never changed even after a few minutes left idle on the final page. Verdict: not a large saving with a slight decrease in browser rendering speed, worth it if you are ram limited.
1. With Firefox up and running, type about:config and hit enter.
2. Find “browser.sessionhistory.max_total_viewers� and instead of the -1 setting, change it to 0 and hit Enter.
3. Restart your browser.
Network Hack:
This next group of hacks all relate to the network.http group in about:config. Basically these various options open up your network connection to Firefox, permitting it to access information online as quickly as your connection will permit you. Since the majority of my readers utilize broadband connections, this will benefit you, 56k you are tough out of luck, sorry. To implement these hacks, perform the following steps.
1. With Firefox up and running, type about:config and hit enter.
2a. Find the entry called “network.http.pipelining� and set it to “true�.
2b. Find the entry called “network.http.proxy.pipelining� and set it to “true�.
2c. Find the entry called “network.http.pipelining.maxrequests� and set it to 16-32, at your digression.
3. Restart your browser.
Cache Hack:
This next hack deals with the memory Firefox uses as cache. In the default setting, Firefox will adjust the cache size to fit however many pages you have open. While this is useful, if you tend to only have a few pages open at a time, you can manually reduce the setting to a specified amount at the cost of reducing performance when Firefox runs out of cache. To implement this hack, follow these steps.
1. With Firefox up and running, type about:config and hit enter.
2. Right click on the new page and select New -> Integer.
3. In the pop-up window, type in “browser.cache.memory.capacity�. In the following pop-up window, specify how many Kb of ram you want to dedicate to the cache, I selected 32768(32Mb). I suggest a number between 16Mb and 64Mb, anything lower and performance will suffer, anything higher is excessive. Here you should experiment, or don’t bother if it worries you.
4. Restart your browser
Download Manager Hacks:
This next group of hacks deal with the download manager in Firefox. For those of you that don’t use the Firefox download manager, skip this section. I don’t know about you, but I personally hate the download manager, it is annoying and generally a distraction when it pops up with its messages and warning, so, let’s do away with it. Follow these steps to tweak/destroy your manager.
1. With Firefox up and running, type about:config and hit enter.
2. Take your pick of the following attributes to modify.
3a. browser.download.manager.showAlertInterval at default shows the alert message for 2000 milliseconds or 2 seconds. I personally set it to 500 milliseconds; all I need is a quick blurb telling me my download is done.
3b. browser.download.manager.openDelay at default opens up the download manager immediately, which can be a big pain if you are downloading 10Kb files to your desktop, you don’t need that annoying manager to pop up. I have this guy set on 30,000 milliseconds or 30 seconds. If a file is larger than 30 seconds of download time, I might want to watch its progress.
3c. browser.download.manager.closeWhenDone at default is set to false so that your manager doesn’t close itself. I set it to true just to get this thing out of the way the moment it is done, I like to watch progress, but I don’t need to waste space or the time to close it.
3d. browser.download.manager.flashCount at default flashes the download manager icon in your taskbar for 2 seconds, I prefer zero seconds to reduce annoyance, adjust to your preference.
4. Restart your browser.
More on the site, great article.

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You might still remember the little firefox tweak that reducedmemory usage when minimizing firefox. Gomeler.com has..